Glycosphingolipids keep signaling in top-Notch condition

Glycosphingolipids keep signaling in top-Notch condition

C ell surface proteins are absolutely essential to activating the Notch signaling pathway, but the lipids that surround them in the plasma membrane have a signifi cant infl uence too, say Hamel et al. (1). Notch receptor ligands (Delta and Serrate in fl ies) are transmembrane proteins that bind receptors on the surface of neighboring cells. Mysteriously, the ligands must be endocytosed before t...

comparative study of gender representation in top notch and ili series

esl/efl books play a crucial role in shaping language learners worldview of gender roles in society. the present study investigated the status of sexism in two sets of efl textbooks, one developed by non-native iranian authors (ili series) and the other by native authors (top notch series). first, two books from each series was selected randomly. then, a quantitative analysis was carried out wi...

Investigating Metapragmatic Information in Language Teachers’ Books: A Case of Top Notch

Pragmatic aspect of second language (L2) as a component of communicative competence has recently received more attention. Many research studies have investigated the gap between native and nonnative speakers’ command of L2 pragmatics. However, development of L2 pragmatics has been the focus of few studies. In this study, how coursebooks can help both nonnative teachers and learners develop L2 p...

The Representation of Social Actors in Top Notch Textbook Series: A critical discourse analysis perspective

Abstract This study aimed to investigate how English language teaching textbooks portrayed male and female social actors according to their social roles and gender identities. To examine the linguistic representation of male and female social actors and construction of gender identities in ELT textbooks, Top Notch series was selected. To do so, attempts were made to analyze the series in terms ...

How to Keep Your Top Talent